Your kidneys are natural filters, which help you eliminate waste and excessive fluid from the body.

These bean-like organs are located in the lower part of your back, on the each side of the spine.

They contain filtering mechanisms (nephrons), which clean your blood and create urine.

In addition to this, kidneys secrete hormone erythropoietin, which activates synthesis of red blood cells.

Renin is a chemical, generated by your kidneys, which plays a great role in regulation of the blood pressure.

If something goes wrong with the kidneys, your body loses ability to remove waste and excessive water away.

Kidney failure may occur abruptly because of decreased blood supply, kidney stones or as a result of toxic influence of certain medications (high doses of ibuprofen and naproxen, gentamicin or lithium).

In the majority of cases kidney dysfunction develops gradually, during extended period of time.

Chronic renal failure is often associated with poorly managed diabetes, uncontrolled hypertension, infection, autoimmune disorders and obesity.

The problem is that people frequently don’t even know that their kidneys don’t work properly. The thing is, these organs can compensate dysfunction for a long time. On the other hand, kidney disease usually causes non-specific symptoms, which can be confused with wide variety of other health issues.

Pay attention on these warning signs, which can indicate kidney disease:

#1 Eye puffiness – failed kidneys can’t keep protein in the body. Lack of protein results in the water retention and eye puffiness.

#2 Frequent need to urinate – people with kidney disease usually notice that they want to go more often than earlier, especially at night.

#3 Weakness and concentration problems – as your kidneys lose ability to remove toxic agents from the body, these substances tend to accumulate in the blood, causing extreme fatigue and impairing your concentration. Furthermore, you probably remember that kidneys support production of red blood cells. Unhealthy kidneys can’t perform this function properly. As a result, you may suffer from anemia, which manifests in dizziness, inexplicable tiredness and hair loss.

#4 Swollen legs – excessive fluid is usually stored in the lower extremities, particularly in the feet and ankles. It may be a result of sodium retention, which commonly accompany renal failure.

#5 Loss of appetite – it can be a sign of numerous health problems. Buildup of harmful substances, related to kidney dysfunction, is a frequent reason for reduced appetite.

#6 Skin dryness and itchiness – healthy kidneys keep normal mineral balance, you know. When problems occur with these bean-shaped organs, electrolyte balance can be disturbed that leads to extreme dryness of the skin. Anemia may be also a reason of your permanent want to scratch yourself.

#7 Muscle cramps – kidney disorder causes electrolyte imbalance, resulting in muscle twitching and spasms.